2024
Olfactory Mucosa-Derived Mesenchymal Stem Cells Differentiate Towards a Schwann Cell-Like Phenotype Towards Sourcing for Peripheral Nerve Regeneration
Katelyn Neuman, Abigail N Koppes, Ryan A Koppes
A Pumpless, High-Throughput Microphysiological System to Mimic Enteric Innervation of Duodenal Epithelium and the Impact on Barrier Function
Kyla N Kaiser, Jessica R Snyder, Ryan A Koppes, Abigail N Koppes
Cell Line and Media Composition Influence the Production of Giant Plasma Membrane Vesicles
William Doherty, Sarah Benson, Lisa Pepdjonovic, Abigail N Koppes, Ryan A Koppes
2023
Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological system
Justin A Hayes, Anna W Lunger, Aayushi S Sharma, Matthew T Fernez, Rebecca L Carrier, Abigail N Koppes, Ryan Koppes, Benjamin M Woolston
Impact of Non-Muscle Cells on Excitation-Contraction Coupling in the Heart and the Importance of In Vitro Models
Kirstie Belanger, Abigail N Koppes, Ryan A Koppes
Complex Material Properties of Gel-Amin: A Transparent and Ionically Conductive Hydrogel for Neural Tissue Engineering
Katelyn E Neuman, Aidan Kenny, Lily Shi, Abigail N Koppes, Ryan A Koppes
En route to next-generation nerve repair: static passive magnetostimulation modulates neurite outgrowth
Katelyn Neuman, Xiaoyu Zhang, Caroline Mills, Ryan Koppes, Laura H Lewis, Abigail Koppes
2022
Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro
Adam J Bindas, Kyla N Nichols, Nicole J Roth, Ryan Brady, Abigail N Koppes, Ryan A Koppes
Lactate production can function to increase human epithelial cell iron concentration
Caroline Ghio, Joleen M Soukup, Lisa A Dailey, Andrew J Ghio, Dina M Schreinemachers, Ryan A Koppes, Abigail N Koppes
These organoids have some nerve: Uniting three germ layers in a human gastric model system
Abigail N Koppes, Ryan A Koppes, Kyla N Nichols
2021
Innervated adrenomedullary microphysiological system to model nicotine and opioid exposure
Jonathan R Soucy, Gabriel Burchett, Ryan Brady, Kyla Nichols, David T Breault, Abigail N Koppes, Ryan A Koppes
Parkinson’s disease and the gut: Models of an emerging relationship
Adam J Bindas, Subhash Kulkarni, Ryan A Koppes, Abigail N Koppes
Bioengineering the neurovascular niche to study the interaction of neural stem cells and endothelial cells
Max A Winkelman, Abigail N Koppes, Ryan A Koppes, Guohao Dai
Light irradiation of peripheral nerve cells: Wavelength impacts primary sensory neuron outgrowth in vitro
David Diaz Vera, Jonathan R Soucy, Audrey Lee, Ryan A Koppes, Abigail N Koppes
The effects of low intensity focused ultrasonic stimulation on dorsal root ganglion neurons and Schwann cells in vitro
Daniel M Ventre, Avery Cluff, Christian Gagnon, David Diaz Vera, Ryan A Koppes, Abigail N Koppes
2020
Cholinergic Activation of Primary Human Derived Intestinal Epithelium Does Not Ameliorate TNF-α Induced Injury
Sanjin Hosic, Will Lake, Eric Stas, Ryan Koppes, David T Breault, Shashi K Murthy, Abigail N Koppes
Electroconductive Hydrogels for Tissue Engineering: Current Status and Future Perspectives
Zachary J Rogers, Michael P Zeevi, Ryan Koppes, Sidi A Bencherif
Reconfigurable microphysiological systems for modeling innervation and multitissue interactions
Jonathan R Soucy, Adam J Bindas, Ryan Brady, Tess Torregrosa, Cailey M Denoncourt, Sanjin Hosic, Guohao Dai, Abigail N Koppes, Ryan A Koppes
Cryopreservation and functional analysis of cardiac autonomic neurons
Tess Torregrosa, Sophie Webster, Chiamaka Aghaizu, Jonathan R Soucy, Christopher Bertucci, Leigh Plant, Abigail N Koppes, Ryan A Koppes
Materials and microenvironments for engineering the intestinal epithelium
Jessica Snyder, Chia-Ming Wang, An Qi Zhang, Yuan Li, Joshua Luchan, Sanjin Hosic, Ryan Koppes, Rebecca Lyn Carrier, Abigail Koppes
Recent advancements in microphysiological systems for neural development and disease
Kyla Nichols, Ryan Koppes, Abigail Koppes
Rapid Prototyping of Multilayer Microphysiological Systems
Sanjin Hosic, Adam J Bindas, Marissa L Puzan, Will Lake, Jonathan R Soucy, Fanny Zhou, Ryan A Koppes, David T Breault, Shashi K Murthy, Abigail N Koppes
2019
Glial cells influence cardiac permittivity as evidenced through in vitro and in silico models
Jonathan R Soucy, Jody Askaryan, David Diaz, Abigail N Koppes, Nasim Annabi, Ryan A Koppes
Instrumented Microphysiological Systems for Real-Time Measurement and Manipulation of Cellular Electrochemical Processes
Jonathan R Soucy, Adam J Bindas, Abigail N Koppes, Ryan A Koppes
Neural responses to electrical stimulation in 2D and 3D in vitro environments
Christopher Bertucci, Ryan Koppes, Courtney Dumont, Abigail Koppes
Bioprinting of a cell-laden conductive hydrogel composite
Andrew R Spencer, Ehsan Shirzaei Sani, Jonathan R Soucy, Carolyn C Corbet, Asel Primbetova, Ryan A Koppes, Nasim Annabi
Stabilized Interleukin-4-Loaded Poly(lactic-co-glycolic) Acid Films Shift Proinflammatory Macrophages toward a Regenerative Phenotype in Vitro
Alexis M Ziemba, Anthony R D’Amato, Taylor M MacEwen, Devan L Puhl, Abigail N Koppes, Ryan A Koppes, Michelle R Lennartz, Ryan J Gilbert
2018
Photocrosslinkable gelatin/tropoelastin hydrogel adhesives for peripheral nerve repair
Jonathan R Soucy, Ehsan Shirzaei Sani, Roberto Portillo Lara, David Diaz, Felipe Dias, Anthony S Weiss, Abigail N Koppes, Ryan A Koppes, Nasim Annabi
Bioactive organic rosette nanotubes support sensory neurite outgrowth
Marissa L Puzan, Belete Legesse, Ryan A Koppes, Hicham Fenniri, Abigail N Koppes
Electroconductive Gelatin Methacryloyl-PEDOT:PSS Composite Hydrogels: Design, Synthesis, and Properties
Andrew R Spencer, Asel Primbetova, Abigail N Koppes, Ryan A Koppes, Hicham Fenniri, Nasim Annabi